Box of tissues not included.
Note: submissions have been edited for clarity and length.
Grey's Anatomy, "Losing My Religion," Season 2, Episode 27
If I need a cry, I always watch the Season 2 finale of Grey's Anatomy. Katherine Heigl's emotional performance mixed with "Chasing Cars" by Snow Patrol playing always gets me!
—sophiek47c1a30e0
ABC
Parenthood, every episode of Season 4
I think I ugly cried during every episode of Season 4. The show perfectly depicted an ordinary family dealing with ordinary struggles. There wasn't a sad topic that the show didn't include, so there's a 99.9% chance that it will hit close to home for you in one way or another.
—ggk328
NBC
The Office, "Finale," Season 9, Episode 23
When Michael leaves Scranton, or when the entire series ends, it feels like you are losing friends you've had for years. It's a breakup, but worse, because you're breaking up with a dozen people you have spent several years getting to know. You don't realize how much you've enjoyed your time at Dunder Mifflin until it's over. —emmaw54
NBC
via BuzzFeed/Travel