When Marvel invited Chris Evans to do a screen test for the titular role in Captain America: The First Avenger, he felt the moment was a "fork in the road" because of the anxiety he'd recently begun experiencing, which included "having mini panic attacks on set." So, he said no, but then the studio came back and offered him the role directly. With the help of his family, therapists, and costar Robert Downey Jr., he realized he'd been "making decisions based on fear."
via BuzzFeed/Travel
